Dosage of 6-paradol

6 -Paradol (CAS No. 27113-22-0) is a bioactive phenolic compound belonging to the gingeroid , found notably in Guinea ginger (Aframomum melegueta) , also known as Grains of Paradise . It is recognized for its antioxidant, anti-inflammatory, and aromatic properties , which make it a quality marker in plant extracts , dietary supplements , and nutraceutical formulations .

The 6-paradol assay allows for the evaluation of the active ingredient content in natural ingredients and ensures the standardization of extracts intended for functional or aromatic purposes. This analysis helps guarantee regulatory compliance and the reproducibility of production batches .

Analytical methods: HPLC and LC-MS

The analysis of 6-paradol is performed using high-performance chromatographic techniques:

• HPLC (high-performance liquid chromatography) : reference method for the precise quantification of 6-paradol in complex matrices (plant powders, hydroalcoholic extracts, capsules).
• LC-MS (liquid chromatography coupled with mass spectrometry) : used for specific and sensitive detection , even at low concentrations, and to distinguish related compounds such as 6 -gingerol or 6-shogaol .

These methods guarantee high analytical reliability and comply with ISO 17025 , enabling reproducible and internationally comparable analyses.

Industrial and scientific applications

The dosage of 6-paradol is applicable in several areas:

• Nutraceuticals and food supplements : quality control of standardized extracts of ginger, galangal or grains of paradise.
• Medicinal plants : evaluation of the content of active compounds for therapeutic or aromatic use.
• Research and development : monitoring the stability of phenolic compounds in natural formulations.
• Food processing and flavorings : control of the aromatic composition of ingredients based on ginger or Guinea pepper.

This test can be combined with the measurement of 6-gingerol or 6-shogaol for a complete analysis of the active profile of ginger .

Affected matrices

Our partner laboratories perform 6-paradol assays on:

• Extracts of ginger or grains of paradise
• Dietary supplements (capsules, powders, liquids)
• Essential oils and CO₂ extracts
• Plant-based raw materials and food preparations

Each analytical protocol is adapted to the matrix , the expected concentration level , and the standardization or regulatory compliance requirements .

YesWeLab expertise

At YesWeLab , we work with a network of over 200 partner laboratories in France and Europe , accredited to ISO 17025 and COFRAC , experts in chromatographic analysis of bioactive compounds .

Our scientific team assists you in choosing the most suitable analytical method , selecting the specialized laboratory , and tracking your samples via our digital platform . You thus benefit from a centralized, fast, and transparent process , from requesting a quote to receiving the results.

Since 2020, YesWeLab has been the preferred partner of the nutraceutical, phytotherapeutic and agri-food industries for their quality control and characterization needs of plant compounds .

Order a 6-paradol analysis

Do you want to control the 6-paradol content in your ginger extracts or nutraceutical products?
Submit your request via our platform or contact our scientific team for personalized support .

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