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Digitoxin (cardiac glycoside) dosage

Digitoxin (cardiac glycoside) dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

71-63-6

Description

Digitoxin is a cardiac glycoside belonging to the cardenolide family, naturally present in foxglove leaves (Digitalis purpurea).

Although its use is strictly regulated in the pharmaceutical field, its dosage may prove necessary in environmental, botanical or quality control studies of plant extracts.

Digitoxin assay is an analysis that aims to detect or quantify this potentially toxic molecule in natural or technical matrices. The assay is generally performed by liquid chromatography (HPLC or UPLC), coupled with UV detection or mass spectrometry (LC-MS/MS), allowing highly specific detection even at low concentrations.

 

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