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Dichloromethane dosage

Dichloromethane dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical

CAS No.

75-09-2

Description

Dichloromethane (CAS No. 75-09-2), also known as methylene chloride , is a volatile organic solvent (VOS) widely used in industrial extraction, formulation, and cleaning processes . While effective at dissolving many compounds, it exhibits potential toxicity and high volatility , necessitating rigorous control of its residual presence in finished products and the environment.

Dichloromethane analysis allows for the detection and quantification of its traces in various matrices such as cosmetics, packaging, food products, water, and technical solvents . This analysis is essential to ensure consumer safety and regulatory compliance with European requirements (REACH, CLP, EC Regulation No. 1223/2009 for cosmetics).

Analytical methods: GC-FID and GC-MS

Dichloromethane is analyzed by gas chromatography , with two main approaches depending on the required sensitivity:

  • GC-FID (gas chromatography with flame ionization detection) : a robust and rapid method for the quantitative control of residual solvents in simple matrices.
  • GC-MS (gas chromatography coupled with mass spectrometry) : reference technique offering high molecular specificity and trace detection , suitable for complex matrices (cosmetics, packaging, environmental media).

These methods guarantee reliable and reproducible results , in accordance with international standards (ISO 16000, EN 13649, USP <467>) relating to the measurement of volatile organic compounds.

Industrial and regulatory applications

Dichloromethane measurement is essential for several fields:

  • Cosmetics : verification of the absence of residual chlorinated solvents in formulations, in accordance with EC Regulation 1223/2009.
  • Agri-food and packaging : control of materials in contact with foodstuffs to prevent solvent migration.
  • Environment : monitoring of air, water or soil pollution by dichloromethane in impact studies.
  • Chemical and pharmaceutical industry : validation of extraction and purification processes according to good manufacturing practices (GMP).

This service can be combined with the measurement of volatile organic compounds (total VOCs) or the measurement of chloroform for broader control of halogenated solvents.

Affected matrices

Our partner laboratories perform dichloromethane analysis on a wide variety of matrices:

  • Cosmetic products, liquid formulations or creams
  • Plastic packaging and polymer films
  • processed food products or plant extracts
  • Water, air or soil samples
  • Technical solvents and industrial effluents

Each protocol is adapted to the matrix being studied and to the regulatory detection thresholds , allowing for an interpretation that complies with environmental and safety requirements.

YesWeLab expertise

At YesWeLab , we work with an international network of over 200 partner laboratories , located in France, Europe and internationally , rigorously selected for their technical expertise , state-of-the-art equipment and ISO 17025 and COFRAC accreditations .

Our scientific team supports you at every stage: defining the analysis protocol , choosing the appropriate laboratory , tracking samples , and validating results . Thanks to our digital platform , you can centralize your requests , obtain a quick quote , and track your analyses online .

Since 2020, many manufacturers, distributors and engineering firms have trusted us to guarantee the safety, compliance and quality of their solvent analyses.

Order a dichloromethane analysis

Do you want to monitor the presence of dichloromethane in your products, packaging or environmental matrices?
Submit your request via our platform or contact our scientific team for personalized support .

→ Add to quote now to get a quick and accurate quote.

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