Cynarin (CAS No. 30964-13-7) is a hydroxycinnamic acid derived from caffeic acid, naturally present in artichoke leaves (Cynara scolymus). Known for its choleretic, hepatoprotective and digestive properties, cynarin is widely used in the formulation of dietary supplements aimed at supporting liver function or promoting digestive elimination.
Cynarin assay is a key analysis for standardizing artichoke-based plant extracts, verifying ingredient compliance and ensuring consistent efficacy in nutraceutical products.
Why measure cynarin?
Cynarin is often used as a quality marker in botanical formulations. Its dosage allows:
- Accurately quantify artichoke extracts used in wellness supplements or formulations
- Check the content of active ingredients claimed on the labeling or claims
- Compare supplier batches or extract stability over time
- Guarantee the reproducibility of the expected effects (action on digestion, bile, hepatic detox)
The dosage is particularly recommended for players in the nutraceutical sector, distributors of plant ingredients, pharmaceutical laboratories, as well as natural health brands wishing to develop formulas based on Cynara scolymus.
Proposed analytical methods
Cynarin analysis is generally carried out using two reference techniques:
- HPLC-DAD: High-performance liquid chromatography with UV detection. Allows the specific separation and quantification of cynarin, even in the presence of other phenolic acids.
- LC-MS: liquid chromatography coupled with mass spectrometry, recommended for low concentration assays or in complex matrices.
These methods generally require prior hydroalcoholic or aqueous extraction depending on the nature of the product (powder, dry extract, capsule, liquid).
Affected matrices
Cynarin dosage can be carried out on numerous matrices from plants or finished products:
- Standardized dry extracts of artichoke
- Nutraceutical capsules, tablets or powders
- Herbal oral solutions or syrups
- Botanical ingredients for dietary supplements
- Raw or processed plant raw materials
Industrial applications
This test is particularly suitable for the following uses:
- Formulation and quality control of hepato-digestive supplements
- Validation of regulatory compliance (minimum levels)
- Standardization of plant active ingredients
- Evaluation of the stability of extracts over time or under aging conditions
- Optimization of extraction processes in product R&D
Why choose YesWeLab for cynarin analysis?
At YesWeLab, we select partner laboratories specialized in phytochemistry, capable of guaranteeing accurate, reliable analysis that complies with current standards. The majority of our partners are ISO 17025 certified or COFRAC accredited, which ensures optimal traceability of results.
With our platform, you benefit from:
- Personalized support from our scientific experts
- Access to cutting-edge techniques such as LC-MS/MS or HPLC-DAD
- Rapid handling of your requests via a simple and intuitive digital tool
- Comprehensive and actionable reports for your quality, marketing or regulatory files
Recommended internal links
To complete your analytical strategy around phenolic acids and plant extracts for hepatic purposes, you can also consult:
- Chlorogenic acid dosage – another phenolic derivative present in artichoke
- Total polyphenol assay – for a global assessment of antioxidant capacity
- Silymarin Dosage – Milk Thistle Extract Used in Combination with Artichoke for Liver Health
Contact our team
Since 2020, YesWeLab has been supporting companies in the nutraceutical and phytotherapeutic sector in the centralized management of their laboratory analyses. Our goal: to save you time, secure your product launches, and guarantee the quality of your herbal formulations.
Need a quote? Contact us today through our platform.
