Cyclopentasiloxane dosage

Cyclopentasiloxane (D5, CAS No. 541-02-6) is a volatile silicone widely used in cosmetic and personal care formulations for its emollient, texturizing, and smoothing properties . Present in creams, lotions, oils, deodorants, and hair products , it provides a feeling of softness and facilitates the application of formulas.

However, its high volatility and environmental persistence justify strict control of its concentration in finished products. Cyclopentasiloxane dosage ensures regulatory compliance according to the recommendations of the ECHA (European Chemicals Agency) and Regulation (EC) No 1223/2009 on cosmetics.

Analytical methods: GC-FID and GC-MS

Cyclopentasiloxane analysis is performed by gas chromatography , allowing for specific and sensitive detection of volatile silicone compounds:

• GC-FID (gas chromatography with flame ionization detection) : suitable for the overall quantification of silicones in simple matrices.
• GC-MS (gas chromatography coupled with mass spectrometry) : allows precise identification and quantification at trace levels in complex or multi-component formulations.

These methods offer high reproducibility , while respecting good analytical practices (GLP) and ISO 17025 standards applicable to chemical analysis laboratories.

Industrial and regulatory applications

Cyclopentasiloxane dosage is essential in several areas:

• Cosmetics and dermopharmacy : quality control of formulations containing volatile silicones (D4, D5, D6).
• Regulatory safety : verification of product compliance with REACH restrictions, particularly on persistent, bioaccumulative and toxic compounds (PBT/vPvB).
• Environmental assessment : quantification in industrial effluents and environmental impact studies.
• Control of packaging and materials : verification of silicone migration in packaged products.

This service can be complemented by the measurement of cyclotetrasiloxane (D4) or cyclohexasiloxane (D6) for a complete analysis of the silicone profile of a formulation.

Affected matrices

Our partner laboratories perform cyclopentasiloxane assays on various types of matrices:

• Cosmetic products (creams, sprays, lotions, oils, deodorants, hair care products)
• Formulation ingredients and raw materials
• Technical or contact food products (on specific request)
• Industrial effluents and manufacturing residues

Each protocol is tailored to the client's matrix , expected content , and regulatory objectives

YesWeLab expertise

At YesWeLab , we work with an international network of over 200 partner laboratories , located in France, Europe and internationally , rigorously selected for their expertise in chemical analyses , their ISO 17025 and COFRAC accreditations , and their ability to meet the strictest regulatory requirements.

Our scientific team will assist you in choosing the analytical protocol , selecting the most suitable laboratory , and providing comprehensive tracking of your samples via our digital platform . You can centralize your requests , obtain quick quotes , and monitor your analyses in real time .

Since 2020, many cosmetic formulators, manufacturers and distributors have trusted us to guarantee regulatory compliance and analytical quality of their products.

Order a cyclopentasiloxane analysis

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