Chrysin (flavone) dosage

Chrysin is a flavone naturally present in several plants, notably passionflower (Passiflora incarnata), certain flower species, and propolis. Recognized for its antioxidant and anti-inflammatory properties, as well as its potential role in hormonal modulation, it plays a significant role in the nutraceutical, natural cosmetic, and phytotherapeutic sectors. Its analysis allows for verification of the purity, concentration, and standardization of plant extracts or flavone-rich formulations.

The importance of chrysin assay for industry

Chrysin assays address strategic needs for manufacturers, formulators, and R&D laboratories. They ensure consistency in the composition of plant extracts and prevent significant batch-to-batch variations, which is essential for the reliability of nutraceutical and phytotherapeutic products. In dietary supplements, chrysin is often used for its antioxidant or soothing effects; its assay guarantees compliance with claims related to active ingredient content.

This dosage is also essential for regulatory approval and labeling. Control bodies and brands require precise quantification to ensure that the stated content matches reality, particularly in concentrated or standardized extracts. For cosmetic formulations, chrysin is a valuable active ingredient thanks to its calming and protective properties; its dosage allows for optimization of the formulation and the level of incorporation.

Finally, chrysin analysis is part of the stability studies conducted by manufacturers. Some plant extracts may exhibit changes in their polyphenolic profile over time; analytical monitoring of chrysin then helps to verify changes in concentration, potential degradation of the compound, or the effectiveness of preservatives.

Available analytical methods

The chrysin assay is carried out using chromatographic techniques recognized for their robustness and precision.

High-performance liquid chromatography (HPLC) is the most common method for quantifying chrysin in plant matrices or dietary supplements. It allows for good separation of polyphenolic compounds and reliable quantification thanks to appropriate UV detectors.

LC-MS or LC-MS/MS offers increased sensitivity and optimal selectivity. This technique is recommended for complex matrices such as propolis, multi-active hydroalcoholic extracts, or flavonoid-rich formulations. It also allows for precise identification in the presence of derivatives or natural interferences.

Analyzed matrices

Chrysin assay can be applied to a wide range of samples:

• passionflower extracts
• propolis (raw, purified, glycerinated or hydroalcoholic)
• standardized vegetable powders
• capsules, tablets, nutraceutical liquids
• Ayurvedic or phytotherapeutic preparations
• natural cosmetic products incorporating flavones
• plant matrices intended for R&D

Further analyses recommended

For a complete characterization of extracts and formulations rich in polyphenols, the following analyses are often associated with chrysin measurement:

• total flavonoid content
• assay of apigenin and its derivatives
• luteolin dosage
• Catechin assay by HPLC or LC-MS

Why have chrysin analyzed at YesWeLab?

At YesWeLab , chrysin analysis is entrusted to rigorously selected, specialized partner laboratories, most of which are ISO 17025 accredited or COFRAC certified. Each request is directed to the most suitable laboratory based on the matrix, technical requirements, and desired detection limits. Our scientific team supports manufacturers in defining their needs, choosing the method, interpreting the results, and optimizing quality controls.

Our digital platform simplifies the entire process: requesting a quote, submitting samples, tracking analysis, and receiving results. Since 2020, numerous manufacturers, plant extractors, formulators, and R&D laboratories have trusted us to manage their analyses.