Chamaemeloside dosage

Chamaemeloside is a flavonoid glycoside naturally present in chamomile (Chamaemelum nobile and Matricaria chamomilla). This bioactive compound belongs to the family of polyphenols, known for their antioxidant, soothing, and anti-inflammatory properties. Its presence contributes to the pharmacological and functional properties of chamomile, which is widely used in herbal medicine, cosmetics, and nutraceuticals.

The dosage of chamaemeloside allows for the precise quantification of this marker in plant extracts or complex formulations, guaranteeing the quality, authenticity and conformity of the ingredients used in the finished products.

Principle of chamaemeloside dosage

The assay is based on high-performance chromatographic methods suitable for the analysis of glycosylated flavonoids:

• HPLC-DAD (high performance liquid chromatography with diode array detection) : reference method for the separation and quantification of flavonoids in plant extracts.
• LC-MS/MS (liquid chromatography coupled with tandem mass spectrometry) : a technique offering high sensitivity and enhanced specificity, allowing the detection of chamaemeloside even in complex matrices.

These methods guarantee reliable, reproducible results that comply with nutraceutical and cosmetic industry standards.

Industrial applications

The analysis of chamaemeloside is strategic for several sectors:

• Nutraceuticals : control of chamomile extracts and enriched food supplements, in order to guarantee their effectiveness and regulatory compliance.
• Cosmetics : evaluation of the chamaemeloside content in active ingredients included in creams, lotions, soothing or anti-inflammatory treatments.
• Phytotherapy : standardization of chamomile extracts to ensure consistent quality of preparations used in traditional or modern medicine.
• Research and development : identification of the pharmacological role of chamaemeloside in the biological properties of chamomile and optimization of extraction processes.

Affected matrices

Matrices typically analyzed for chamaemeloside assay include:

• Chamomile extracts (aqueous, hydroalcoholic or glycerin)
• Herbal food supplements
• Standardized powders and dry formulations
• Cosmetic products (creams, serums, soothing lotions)
• Vegetable oils or macerates containing chamomile

Quality and compliance issues

The quantification of chamaemeloside responds to several strategic challenges:

• Authenticity of extracts : detection of possible adulterations or falsifications in chamomile extracts.
• Standardization : guarantee of a constant content of bioactive flavonoids, essential for the efficacy and reproducibility of products.
• Regulatory safety : compliance with current standards for food, nutraceutical and cosmetic products.
• Product promotion : highlighting the richness in specific flavonoids as an argument for differentiation and quality.

YesWeLab support

YesWeLab provides its network of partner laboratories, specialized in the chromatographic analysis of flavonoids and polyphenols. The majority of our partners are certified and accredited (ISO 17025, COFRAC), guaranteeing the reliability of our results.

With YesWeLab, you benefit from:

• Quick online submission of your samples via our digital platform
• Real-time monitoring of the progress of your analyses
• Results that meet international standards and are tailored to your industrial requirements
• Personalized scientific support for choosing the most relevant method (HPLC or LC-MS/MS)

Related analyses

• Total flavonoids assay
• Apigenin dosage
• Luteolin dosage
• Vitexin dosage
• Polyphenol dosage