Calprotectin dosage

Calprotectin (CAS No. 83702-47-8) is a protein of the S100 family, expressed by activated neutrophils, monocytes and macrophages. It plays a key role in the body's immune defense mechanisms. In both animals and humans, calprotectin is now recognized as a non-invasive biomarker of intestinal inflammation, and finds numerous applications in veterinary diagnosis, therapeutic monitoring, and digestive health control.

Why measure calprotectin in animal health?

Calprotectin testing is particularly useful for:

• Detect or monitor gastrointestinal inflammation in animals (enteritis, colitis, IBD)
• Assess the inflammatory state in infectious or chronic contexts
• Monitor the effectiveness of veterinary treatments (anti-inflammatories, probiotics, specialized diets)
• Develop or validate innovative veterinary products (functional foods, supplements, probiotics)
• Conduct preclinical clinical studies on animal models

It is an indirect diagnostic tool, without resorting to invasive methods, allowing reliable quantification of local inflammation in the digestive tract.

Available analysis methods

The dosage of calprotectin is based on specific analytical biology techniques, recognized for their sensitivity and reproducibility:

• ELISA (enzyme-linked immunosorbent assay) method: a widely used enzyme-linked immunosorbent assay for detecting calprotectin in animal biological matrices. It allows for precise quantification using validated kits.
• Spectrophotometry: used in addition or in adapted formats for absorbance measurement after enzymatic reaction, according to standard protocols.

These methods allow us to work on animal stool samples, biological extracts or formulations for veterinary use.

Affected matrices

The calprotectin assay applies to various animal matrices, including:

• Animal stools (dogs, cats, ruminants, horses, etc.) for non-invasive diagnosis
• Finished veterinary products (enriched formulas, probiotics, prebiotics)
• Raw materials or biological extracts in a formulation or research context

Industrial applications

Areas of application of calprotectin assay in animal health include:

• Quality control of veterinary products intended for digestive health
• Bioavailability and mechanism of action studies in preclinical trials
• Development of functional veterinary formulations
• Validation of health claims in the context of nutritional or nutraceutical products for animals
• Veterinary research on inflammatory mechanisms

Why choose YesWeLab for your animal health analyses?

YesWeLab relies on a network of selected partner laboratories, most of which are ISO 17025 certified and/or COFRAC accredited, to offer you a rigorous, fast analytical service tailored to your specific needs. Thanks to our digital platform, you can:

• Submit your samples online in just a few clicks
• Get a personalized quote within 24 to 48 hours
• Track the processing and results of your analyses in real time
• Benefit from the support of our expert scientific team in animal health

We help you choose the analysis method that best suits your matrix, budget, and objectives, whether for quality control, product development, or applied research.

Contact us

Since 2020, YesWeLab has been supporting animal health manufacturers and professionals in outsourcing and optimizing their analyses. Our mission: to save you time, guarantee quality, and facilitate the management of your laboratory projects.

Need a quick quote? Add this service to your cart or contact our scientific team directly.