Butyric acid dosage

Butyric acid (or butanoic acid, CAS 107-92-6) is a short-chain fatty acid (SCFA) naturally produced in the human colon by the fermentation of dietary fiber by the gut microbiota. It is also found in many fermented food products, including aged cheeses, butter, fermented plant materials, as well as nutritional supplements and probiotic formulations.

Thanks to its anti-inflammatory, energetic (for colonic epithelial cells) and immunomodulatory properties, butyric acid has attracted considerable interest in the fields of functional nutrition, fermented dairy products, and clinical studies on the microbiota.

Why measure butyric acid?

Butyric acid dosage is a key marker for:

• Assessing the quality and concentration of volatile fatty acids in fermented products
• Characterize the fermentation activity of probiotic raw materials or ingredients
• Supporting health claims related to gut microbiota and digestion
• Monitoring the progress of fermentation during food manufacturing processes
• Quantify butyrate content in nutritional extracts or supplements

It is also a useful parameter in clinical research or scientific studies on the effects of prebiotic and symbiotic fibers.

Available analytical methods

YesWeLab offers several analytical techniques to quantify butyric acid accurately, depending on the nature of the matrix and the expected level of detection:

• GC-FID (gas chromatography with flame ionization detection): reference method for volatile fatty acids, preceded by a derivatization/esterification step to improve detection.
• GC-MS (gas chromatography coupled with mass spectrometry): ideal for complex matrices or low concentrations, with better sensitivity.
• HPLC (high performance liquid chromatography): Used in certain contexts where an alternative to GC is needed.

All methods can be adapted according to your specific requirements, or validated according to quality standards (ISO, internal standards, customer specifications).

Affected matrices

The determination of butyric acid can be carried out on a wide range of matrices:

• Dairy products: mature cheeses, yogurts, fermented milks
• Butters and natural fats
• Fermented raw materials: yeasts, plants, fermentation substrates
• Food supplements: butyrate-based probiotics, capsules, powders
• Samples from clinical trials or experimental digests

Our experts will advise you on the best method based on your sample type.

Sectors of activity concerned

This analysis is aimed at manufacturers, formulators and laboratories in the following sectors:

• Human food: organoleptic quality, fermentation, dairy products
• Functional nutrition and nutraceuticals: products targeting digestive health
• Research on the intestinal microbiota
• Fermented or symbiotic foods: kombucha, kefir, lacto-fermented vegetables, etc.
• Cosmetics or animal health, within the framework of integrative approaches to the microbiome

Why choose YesWeLab for your analyses?

At YesWeLab, we rely on a network of more than 200 specialized partner laboratories, selected for their scientific rigor and accreditations (ISO 17025, COFRAC, GLP). Thanks to our secure digital platform, you benefit from:

• From a simplified order of analyses
• Transparent monitoring of deadlines and results
• Personalized scientific support
• Negotiated and competitive rates

Recommended Related Analyses

• Propionic acid dosage
• Volatile fatty acid (VFA) profile

Need a butyric acid dosage?

Add the analysis to your quote or contact our scientific team. We will assist you in choosing techniques and interpreting results in line with your nutritional, regulatory, or R&D objectives.