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Acetylsalicylic acid dosage

Acetylsalicylic acid dosage

Technique(s)
Categories: ,
Sector of activity
Expertise

Physicochemical, Nutritional

CAS No.

50-78-2

Description

Acetylsalicylic acid , better known as aspirin, is a derivative of salicylic acid widely used for its anti-inflammatory, analgesic, and antipyretic properties. Although primarily used in pharmaceuticals, it is also found in some dietary supplements, herbal formulations, and products for technical or research purposes.

Its dosage is essential for quality control, the standardization of plant extracts (particularly for anti-inflammatory purposes), as well as the verification of experimental formulations in innovative sectors such as nutraceuticals.

Analytical methods available: HPLC-DAD and LC-MS

The dosage of acetylsalicylic acid is carried out by liquid chromatography:

  • HPLC-DAD (High Performance Liquid Chromatography with UV/diode array detection): reference method for the analysis of active substances in plant or semi-complex matrices.
  • LC-MS (Liquid Chromatography coupled with Mass Spectrometry): used for matrices with low concentration or requiring high specificity.

Depending on the analytical objectives, monitoring of the degradation into salicylic acid can also be carried out to assess the stability of the molecule over time.

Why measure acetylsalicylic acid?

The dosage of this compound is useful in several industrial or regulatory contexts:

  • Checking the actual composition of a food supplement
  • Control of the authenticity of plant extracts, in particular those from Salix alba (white willow) or other plants rich in salicylates
  • Formulation control for innovative or technical products (cosmeceutical, nutraceutical, dermo-cosmetic)
  • Stability studies or development of investigational products containing salicylate derivatives
  • Assessment of the risk of exceeding regulatory thresholds in certain contexts of active ingredients or residues

Affected matrices

Our partner laboratories have the expertise and equipment necessary to analyze acetylsalicylic acid in a wide variety of matrices:

  • Medicinal plant extracts rich in salicylates
  • Research or development formulations
  • Nutraceutical powders, capsules or tablets
  • Experimental or semi-finished products
  • Technical cosmetics or formulation prototypes

Adapted extraction and purification protocols ensure reliable quantification, even in the most complex matrices.

Areas of application

The dosage of acetylsalicylic acid concerns several industrial sectors:

  • Nutraceuticals: securing formulations combining plant extracts and natural active compounds
  • Functional nutrition: validation of the absence or controlled presence of salicylate derivatives
  • Medicinal plants: standardization of extracts from willows or other natural sources of salicylates
  • Cosmetics and dermo-cosmetics: verification of technical formulas with soothing or exfoliating action
  • Applied research: formulation, stability, bioavailability, preclinical testing

YesWeLab: a network of experts at the service of your analyses

YesWeLab provides you with a unique digital platform to order, centralize, and track your analyses. We collaborate with a network of ISO 17025-accredited or equivalent laboratories specializing in physical chemistry and chromatography.

Our scientific team supports you every step of the way: from method selection and interpretation of results to customizing the analytical offering. Each request is handled confidentially, with rigor and responsiveness.

Further analyses recommended

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Need to verify the acetylsalicylic acid concentration in your extracts or products? Describe your goals and specific requirements. YesWeLab will support you with a personalized, fast, and industry-standard analytical service.

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